Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier.
MilliporeSigma™ Calbiochem™ BMP Inhibitor II, DMH1
The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Caspase-8 Inhibitor I, Cell-Permeable
The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor IV, SB-216763
A cell-permeable (aryl,indole) maleimide compound that acts as a potent, selective, ATP-competitive inhibitor of GSK-3 activity (Ki
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Inhibitor IV, CPTH2
A cell-permeable thiazolyl-hydrazone compound that inhibits the acetylation of histone H3 by recombinant human Gcn5 in a substrate-competive manner, while exhibiting little activity against rhGcn5 autoacetylation
MilliporeSigma™ Calbiochem™ Indirubin-3'-monoxime
A potent, reversible, and ATP-compatible inhibitor of GSK-3β (glycogen synthase kinase 3β), Cdk1 (cyclin-dependent kinase1) and Cdk5 (IC50 = 22 nM, 180 nM, and 100 nM, respectively).
MilliporeSigma™ Calbiochem™ MPTP Hydrochloride
A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism
MilliporeSigma™ Calbiochem™ MAP Kinase Inhibitor Set I
The MAP Kinase Inhibitor Set I controls the biological activity of MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Akt Inhibitor
The Akt Inhibitor controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt
A potent cell-permeable activator of cAMP-dependent protein kinase (PKA).
MilliporeSigma™ Calbiochem™ Mecamylamine Hydrochloride
A potent, nonselective, and noncompetitive antagonist of nAChRs (IC50 = 640 nM
MilliporeSigma™ Calbiochem™ GTS-21 Dihydrochloride (DMBX-A)
A partial agonist selective for α7 nAChRs (EC50 = 10
MilliporeSigma™ Calbiochem™ p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5
The p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5 controls the biological activity of p75NTR. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ 12/15-Lipoxygenase Inhibitor, ML351
A cell-permeable, highly potent, selective, active site directed, mixed type inhibitor of lipoxygenase-12/15 (IC50 = 200 nM for human).
MilliporeSigma™ Calbiochem™ Pifithrin-μ
Pifithrin-μ, CAS 64984-31-2, is a cell-permeable inhibitor of p53 interaction with Bcl-xL and Bcl-2. Inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.